Surface Modifications of Liposomes

Surface Engineering of Liposomes for Stealth Behavior

Liposomes are used as a delivery vehicle for drug molecules and imaging agents. The major impetus in their biomedical applications comes from the ability to prolong their circulation half-life after administration. Conventional liposomes are easily recognized by the mononuclear phagocyte system and are rapidly cleared from the blood stream. Modification of the liposomal surface with hydrophilic...

Nanoparticle-assisted surface immobilization of phospholipid liposomes.

Phospholipid liposomes (100-200 nm diameter) are deposited onto solid substrates after stabilizing them against fusion with the solid by allowing charged nanoparticles to adsorb at approximately 25% surface coverage. The immobilized vesicles remain stable over a period of days. Epifluorescence imaging shows that they diffuse freely over surfaces with the same charge but adsorb tightly onto surf...

Surface interactions between nanocrystal cellulose and liposomes

Surface modifications of glass-reinforced hydroxyapatite composites.

Surface modifications of glass-reinforced hydroxyapatite composites immersed in a simulated physiological solution were studied using X-ray photoelectron spectroscopy, scanning electron microscopy and energy dispersive X-ray spectroscopy. In the first stages of the apatite formation process, calcium and silicon ions were leached out from the surface of the composites. After 12 days of immersion...

A Study of Effects of Different Surface Modifications of MWCNTs on their Adsorption Capacity of Benzene and Toluene

Multi-Walled Carbon Nanotubes (MWCNTs) surfaces were serially modified by the annealing treatment under Helium flow at 1000oC, the nitric acid treatment and again the annealing treatment under same conditions and their maximum adsorption capacities for benzene and toluene were measured and analyzed. The unmodified and modified MWCNTs werecharacterized by Fourier Tr...